Prognostic Significance of Small-Artery Structure in Hypertension
نویسندگان
چکیده
منابع مشابه
Prognostic significance of small-artery structure in hypertension.
BACKGROUND The presence of structural alterations in the microcirculation may be considered an important mechanism of organ damage; however, it is not currently known whether structural alterations of small arteries may predict fatal and nonfatal cardiovascular events. METHODS AND RESULTS One hundred twenty-eight patients were included in the present study. There were 59 patients with essenti...
متن کاملSmall artery structure and function in hypertension
It has been known for some considerable time that sustained hypertension changes the circulatory architecture both in the heart and blood vessels. The histopathological alterations are of considerable interest because once they have developed they appear to carry an adverse prognostic risk. In the heart it is apparent that there is hypertrophy. This extends also to the large- and medium-sized b...
متن کاملSmall artery remodeling and significance in the development of hypertension.
The structure of the resistance vessels is altered (remodeled) in individuals with high blood pressure (essential hypertension). The structure is dependent not only on blood pressure but also on blood flow and hormonal environment. Vascular biology is providing increased knowledge of the mechanisms involved and thus contributing to our understanding of the pathophysiology of the disease.
متن کاملReducing pulse pressure in hypertension may normalize small artery structure.
To investigate the relation between the small artery structure and different blood pressure parameters, spontaneously hypertensive rats were treated from 4 to 24 weeks of age (20 weeks in total) with five different antihypertensive therapies: two angiotensin converting enzyme inhibitors (perindopril and captopril), a calcium antagonist (isradipine), a beta-blocker (metoprolol), and a vasodilato...
متن کاملPrognostic significance of left ventricular diastolic dysfunction in essential hypertension.
OBJECTIVES We sought to assess the prognostic value of alterations in left ventricular (LV) diastolic function in patients with essential hypertension. BACKGROUND Alterations in LV diastolic function are frequent in patients with hypertension, even in the absence of LV hypertrophy, but their prognostic significance has never been investigated. METHODS In the setting of the Progetto Ipertens...
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ژورنال
عنوان ژورنال: Circulation
سال: 2003
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.0000095031.51492.c5